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Biointerfaces Institute

Lateral Flow Dispensers (Printers)

Overview

Biodot Lateral Flow Dispensers (LFDs) are versatile tools for dispensing lines and dots, with either non-contact or contact printing/dispensing techniques. The BI Biodot LFDs feature multiple dispensing channels for non-contact dispensing, each with independent volume control, and programable line length and volume within X, Y and Z axes.

This instrument is mainly used for the in-house creation of point-of-care diagnostic devices, but can be used to dispense a variety of solutions. It can dispense higher viscosity samples (e.g. >100 mPa/s).

The BI has two LFDs and specialized cutter and laminator equipment to fabricate point of care diagnostic strips.

Biodot XYZ3060

is equipped with one Airjet* channel and two nanoliter Biojet** dispensing channels (with ILD5000 in-line degasser) for either non-contact printing. Dispensing area of 470 x 70 mm.

Biodot XYZ3210

is equipped with one Airjet* channel and four nanoliter Biojet** dispensing channels (with ILD5000 in-line degasser and FrontLine) for non-contact printing. It also has a larger deck and is within an enclosed system for better humidity control.

Guillotine Cutter

The CM4000 and CM5000 guillotine-style cutters, with 60 degree angle top stainless steel blades and leading edge sensor, automatically feeds materials for accurate and precise cuts . Easily programmed by a hand-held controller, it is suitable for batch cutting of numerous sample types, including lateral flow tests and biosensors.

Lamination System

The LM5000 lamination system allows for manual assembly of lateral flow test strips, by facilitating the precise alignment of the membrane, conjugate, and absorbent pads, to create a high quality master test strip card.

*The Airjet dispensing channel uses pressurized air (or nitrogen) to atomize fluid passing through the dispensing nozzle to create a non-contact, quantitative aerosol spray that can generate a dot or line.

  • Line Volumes: 0.1 – 24 uL/cm
  • Line Widths: 0.5 – 10 mm

**The BioJet dispensing channel meters precise amounts of reagent, incorporating the benefits of non-contact dispensing and the ability to program exact drop volumes.

  • Drop Volumes: 2.0 nL to 2.0 uL
  • Line Volumes: 0.5 – 3.0 uL/cm
  • Drop Sizes: >130 um
  • Line Widths: 0.25 – 2.55 mm

Instrument
Uses

  • Printing in microliter amounts (Airjet) or nanoliter amounts (Biojet)
  • Microarrays
  • Biosensors
  • Lateral flow assays
  • Point-of-care diagnostics

Sample
Requirements

  • Compatible printing solutions, aqueous or most organic solvents (no suspensions)
  • FIltered samples are recommended
  • Coated-glass slides or cellulose/Nitrocellulose membranes

System
Requirements

  • Printing materials must be pre-approved by BI Staff

Other printing instruments are also available. Applications can be contact or non-contact.