Skip to McMaster Navigation Skip to Site Navigation Skip to main content
mcmaster university logo McMaster logo

Biointerfaces Institute

Dynamic Light Scattering with Zeta Potential

Overview

The Zetasizer Nano ZS (Zen 3600) is a high performance particle and molecular size analyzer that uses dual angle Dynamic Light Scattering (DLS) with Non-Invasive Back-Scattering (NIBS) optics.

The system can also incorporate molecular surface charge information via its Zeta-Potential analyzer.

Suitable for measurement of size, molecular weight, mobility, and zeta potential of dispersed particles and molecules in solution.

Instrument
Uses

  • Particle Characterization
  • Electro-kinetic Potential
  • Measure Viscosity

Sample
Requirements

  • Sample: 1 mL of sample, sized 0.3 nm to 10.0 um
  • A suitable sample concentration (conc.) in relation to particle size:
Size Minimum Conc.
<10 nm 0.5 mg/mL
10-100 nm 0.1 mg/mL
100nm-1um 0.01 mg/mL
>1um 0.1 mg/mL

System
Requirements

  • Samples must be contained within compatible cuvettes